How Does HGH Change Your Face and Skin?

HGH deficiency causes numerous skin-related health issues. Optimal HGH levels, on the other hand, confer numerous proven skin health benefits for a more vibrant, more youthful appearance.

Learn about the effects of HGH on your skin and face. Find out if HGH supplementation through hormone replacement therapy (HRT) can make you look younger or cause adult acne.

Does HGH improve skin health?

HGH is vital for skin health.

But before we get into how HGH improves skin health, let’s first explore what happens to patients who have been diagnosed with growth hormone deficiency (GHD).

How do low HGH levels damage the skin?

One study examining the effects of GHD on skin health in women, published in the Journal of the European Academy of Dermatology and Venereology, found that low GH levels are tied to decreased skin hydration and lower sebum production. The sebum is an important protective coating on the skin that protects it from damage.

Similarly, patients with GHD also experience less skin elasticity. Elasticity, which describes the skin’s ability to bounce back into place after stretching, is one of the keys to maintaining plump, youthful-looking skin.

Lowered HGH levels are a natural feature of the aging process, but you don’t have to accept HGH deficiency. Numerous therapies and supplements are demonstrated to boost HGH levels, including HRT in some cases.

Now that we’ve established some – but not all – of the negative skin health effects of growth hormone deficiency, let’s explore what skin health benefits HGH actually confers, and how hormone replacement therapy (HRT) helps patients safely and effectively elevate their levels of this important hormone.

Can human growth hormone tighten your skin?

Firming up, or tightening, the skin is one of the prime ways to reverse the hands of time and look, potentially, decades younger than your chronological age.

Optimizing HGH levels is one of the key ways to tackle the loose skin that often accompanies the aging process. In fact, skin tightening is one of the biggest draws of HGH replacement therapy, as explained in News Medical:

“Anything that may reduce wrinkles, tighten saggy skin, decrease body fat, increase lean muscle mass, strengthen bones, and boost mood, while giving you plenty of energy and improving sex drive, is a no-brainer.”

As we age and HGH levels drop along with other important hormones, the skin tends to become thinner as the epidermis (the outer layer) fades. HGH, though, increases skin thickness, based on clinical research.

In addition to tightening the skin, HRT with synthetic recombinant human growth hormone (rHGH, also known as somatropin) has been shown to increase skin thickness. Research published in the International Journal of Dermatology“Hormone deficient individuals can regain skin thickness with hormone replacement therapy.”

hgh therapy tightens skin
growth hormone is proven to make skin look younger

Does HGH help rejuvenate aging skin?

HGH has the proven capacity to take decades off of a patient’s physical appearance. In addition to tightening and thickening the skin, HGH facilitates skin rejuvenation results through several other mechanisms that we will survey briefly here.

As the most abundant protein in the human body, collagen production is critical for keeping the skin youthful in appearance. As humans age, collagen production decreases, with numerous and significant implications for human health.

With respect to the skin, lower collagen levels lead to dry skin and wrinkles. Suffice it to say that if you’re trying to optimize your skin health, you should aim to achieve therapeutic levels of collagen.

Increasing collagen levels leads to a marked improvement in the appearance and texture of the skin. Clinical research supports the beneficial skin impacts of higher collagen levels. In one study on the benefits of collagen supplementation, for instance, published in the Journal of Drugs in Dermatology, researchers found an “increase skin elasticity, hydration, and dermal collagen density. Collagen supplementation is generally safe with no reported adverse events.”

The consumer market is awash in products either containing collagen or promising to boost collagen synthesis in vivo. However, if a hormone imbalance is the root cause of low collagen levels, no other therapeutic intervention is as effective as prescription-grade synthetic HGH (somatopropin).

It’s always better to catalyze endogenous collagen synthesis rather than relying on exogenous supplements containing the protein. To that end, HGH stimulates collagen synthesis based on research published in the Journal of Physiology:

“rhGH administration caused a rise in matrix collagen synthesis in skeletal muscle and tendon… GH/IGF-I may be more biologically important for strengthening the supportive matrix in tissues than for muscle cell hypertrophy in adult human musculotendinous tissue.”

Last but not least on the list of HGH benefits for the skin is that the powerful hormone has been demonstrated to speed skin healing following wounds or burns.

Skin optimization benefits resulting from hormone replacement therapy (HRT) with HGH generally become apparent after two months.

HGH Therapy

Contact us to find out if human growth hormone therapy is right for you.

Can HGH cause acne?

Acne, which develops as a result of “hormonal overstimulation of the pilosebaceous units of genetically susceptible individuals,” is closely linked to HGH levels as well as levels of other hormones that interact with HGH.

As with any shift in the relative levels of interconnected hormones in the body, increasing HGH levels through HRT or natural means may result in acne in some patients. HGH, through interactions with other hormones like insulin-like growth factor 1 (IGF-1), insulin, and glucocorticoids, may “play a major role in the pathogenesis and exacerbation of acne.” Other forms of therapy, such as testosterone replacement therapy (TRT), may also trigger acne.

The good news is that acne resulting either naturally due to hormone imbalance or from HRT with synthetic HGH, in nearly all cases, can be managed effectively in consultation with your endocrinologist (hormone doctor). He or she may adjust your dosage and/or prescribe medications to reduce acne.

How does growth hormone change your face?

It’s well-documented that HGH deficiency in children has been correlated with smaller bones in the face. Excessive HGH can have the opposite effect.

Let’s explore the nuances of HGH’s effect on the face and how HRT patients can avoid these complications.

Does human growth hormone cause your jaw to grow?

Growth hormone is implicated in the growth of facial bones, as explained in the medical journal Diagnostics:

“GH exhibits a positive effect on growth of the cranial base, maxilla, and mandible, especially its ramus, as well as on an increase of facial height.”

Excessive growth hormone in the blood can lead to a condition called acromegaly, characterized by the abnormal growth of the bones in the hands, feet, and face.

Above: a male patient experiencing facial bone growth due to acromegaly

UFC superstar Connor McGregor, who has previously admitted to using HGH (probably illegally without a prescription), has been accused of supplementing due to the apparent change in the structure of his face in recent months as well as his muscle mass increases.

excessive gh in the blood can lead to acromegaly
growth hormone is implicated in the growth of facial bones

How to prevent the side effects of HGH on the face?

Here are the best ways to avoid the potential negative side effects of HGH on the face:

  • Consult with an expert endocrinologist before, during, and after undergoing HRT. Never attempt therapy on your own.
  • Follow your doctor’s instructions to the letter. If you miss a dose, do not double up on your next dose. Simply continue with your regular dosing regimen.
  • Undergo routine blood testing throughout therapy. Your doctor will order routine blood draws for you while receiving HRT to ensure your HGH levels are consistently in the optimal therapeutic range.
  • Only utilize FDA-approved, prescription somatropin (synthetic HGH). Other forms of HGH, such as those available on the black or gray markets, are not only illegal but also dangerous as they often contain added harmful ingredients or doses of HGH that differ from the quantities listed on the label. All of the licensed, regulated HGH formulations we sell at HGH For Men Clinic are fully approved by the FDA.
  • Report any side effects to your doctor such as changes to your skin or face as soon as they appear. He or she will likely adjust your dose or make other changes to your therapeutic protocol to address these issues in a timely manner before they become bigger issues.
  • Do not combine prescription somatropin with over-the-counter “HGH boosters” or other products marketed to increase HGH. These are unnecessary if you are receiving therapy and will likely complicate your progress.


HGH is hugely beneficial for several facets of skin health in individuals who have diagnosed deficiencies, which are common later in life. If you are suffering from sagging, wrinkling, or loose skin, and you have not undergone testing to determine your HGH status, you might have undiagnosed growth hormone deficiency (GHD).

Contact your doctor to learn whether HGH replacement therapy is what the doctor ordered to achieve younger-looking, firmer, thicker skin.

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Brooklyn, New York 11224

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