How to Cycle HGH and Testosterone?

HGH and testosterone cycling is a popular combination among anti-aging enthusiasts as well as athletes looking for a competitive edge. But does it work, is it safe, and is it ultimately worth it?

Read further to learn about the utility of HGH and testosterone cycling and to find out if cycling human growth hormone and testosterone is worth it.

How to cycle HGH and testosterone?

“Cycling” in the context of hormone replacement therapy (HRT) simply means the practice of pausing supplementation and then resuming supplementation at regular, scheduled intervals.

Many athletes believe cycling enhances the net benefits of human growth hormone (HGH) and testosterone while reducing or eliminating any unwanted side effects resulting from therapy. There is some medical literature that supports the cycling hypothesis that we’ll explore here.

As always, you should never attempt an HGH or testosterone cycle without the guidance of an expert endocrinologist (hormone doctor) like the ones at HGH For Men Clinic. Attempting to cycle on your own without medical supervision could result in serious negative health impacts.

Pros and cons of cycling HGH

pros and cons of hgh cyclingEvery decision related to HRT comes with a set of potential advantages as well as downsides. Cycling is no different. So let’s briefly run down some of the pros and cons of cycling HGH that you should consider.

HGH cycling pros:

  • May help save money by cutting monthly expenses for HGH supplies
  • Allows patient to compare and contrast mental and physical health on and off HGH
  • Gives the body a chance to reset and rebalance the other hormones in the body
  • May help competitive athletes pass drug screenings

HGH cycling cons:

  • May result in inconsistent HGH levels in the blood, compromising therapy effectiveness
  • Requires closer monitoring of blood levels to ensure safety
  • May disrupt your daily routine

The most common cycling window for HGH is 8 weeks on with two weeks off before beginning the next cycle. However, your doctor may help design a unique cycling protocol to match your individual needs.

HGH cycling may provide some benefits, but it’s not necessary in most cases. The most important thing to remember is that HGH replacement therapy does not diminish your body’s natural supply of HGH produced in the pituitary gland.

Whereas other hormone therapies such as testosterone replacement therapy (TRT) are more conducive to cycling, most patients don’t necessarily experience profound benefits from cycling HGH.

In most contexts, HGH cycling is done by competitive athletes in combination with other performance-enhancing drugs (PEDs).

How can you benefit from the HGH cycle?

Let’s explore some of the ways you may benefit from an HGH cycle.

You may be able to shave some of the cost of HRT. In general, depending on the amount of HGH utilized, patients tend to spend around $600-$1,500 per month on therapy. In the end, the total may come to around $7,000.

HGH Vial Cost
Saizen© (5 mg) $1,000
Zorbitive (8.8 mg) $15,000
Humatrope® (5 mg) $1,000
Zomactin© (5 mg) $475
Serostim (5 mg) $5,100


Temporarily cycling off of HGH may cut some of these expenses.

If you are a competitive athlete who must submit to scheduled drug screenings, then you might consider cycling off of HGH before your test. Institutions that govern international competition such as the World Anti-Doping Agency (WADA) include HGH on their list of banned substances.

Lastly, if you’re simultaneously receiving testosterone replacement therapy (TRT), you must cycle testosterone to avoid negative side effects. Cycling off of HGH and then resuming at the same intervals as testosterone, while likely not medically necessary, may be a scheduling convenience.

What are the side effects of the HGH cycle?

Due to changes in circulating HGH levels, there may be several side effects associated with cycling. These can include:

  • Sleep issues and other disruptions to your circadian rhythm (sleep-wake cycle)
  • Fluctuations in energy levels
  • Mood swings
  • Changes to libido and sexual function
  • Decreased muscle gains (if you are training)
  • Negative impacts on cardiovascular performance (for athletes)

HGH Therapy

Contact us to find out if human growth hormone therapy is right for you.

HGH cycle details

HGH cycling is, of course, a science. There are very specific protocols that have been developed over many years of clinical trials that you can use in consultation with your doctor to achieve optimal results.

HGH dosage on cycle

The typical HGH dose recommended for most patients in most cases is 0.035 mg/kg of body weight, a calculation your provider will help determine. The daily dose of somatropin should not be more than 2.7 mg.

Everyone responds slightly differently to somatropin. The most important aspect of dosing is getting the HGH levels in the blood into the optimal range.

Normal HGH Levels in Adults
Women 1-14 ng/mL
Men 0.4-10 ng/mL*


This, again, is why you should closely and regularly monitor your blood HGH levels throughout therapy.

the typical recommended hgh dosage
checking your hormone levels is vital during hgh cycle

Length of HGH cycle

The initial HGH cycle should consist of no less than 16 weeks to saturate the organs and tissues with the hormone. Following four months of therapy, you should begin to see the full benefits of therapy. After this initial “loading phase” of 16 weeks, the typical HGH cycling regimen looks like this:

  • Eight weeks of daily HGH injections
  • Two weeks of no HGH injections
  • Eight weeks of daily HGH injections
  • Two weeks of no HGH injections

And so on as long as necessary. The intervals can always be adjusted as you progress through therapy depending on how your body responds to different cycling schedules.

Can you cycle testosterone with HGH?

HGH is, in fact, often paired with testosterone in hormone cycling. Both HGH and testosterone belong to the “anabolic” class of hormones because they stimulate lean muscle growth by way of increased protein synthesis.

These hormones are often paired because HGH and testosterone produce numerous similar benefits for men, such as increased energy levels, added lean muscle mass, reduced body fat, enhanced sleep quality, and restored libido, among others.

As always, you should only undergo HRT – whether that includes HGH, testosterone, or other hormones, or any combination thereof – under the close supervision of a seasoned endocrinologist.


Most patients don’t benefit from cycling HGH because natural HGH production isn’t diminished by HRT with synthetic HGH. However, in certain cases that we’ve explored here, HGH cycling may be beneficial. If you elect for HGH cycling, your endocrinologist will prescribe the appropriate dosing and cycling regimen to meet your goals.

Get in touch

Please get in touch and our expert support team will answer all your questions about HGH therapy.

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Brooklyn, New York 11224

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